By Surgery:
Very limp, saggy breasts can be tightened surgically. This has to be done in a hospital. In some cases simultaneous breast reduction and placing of implants will make sense.

By Liposculpture:
Liposuction with special canulas can reduce heavy, big breasts containing a lot of fat, to normal size. However this will not help against a saggy breast. In this case, surgery is the only option.